Understanding genetic variations in human tissues
WashU-VAI Somatic Mosaicism across Human Tissues (SMaHT) Program Genome Characterization Center
['FUNDING_OTHER'] · WASHINGTON UNIVERSITY · NIH-11083076
This study is looking at how differences in our genes can affect our health and diseases, and it aims to create a detailed map of these differences to help find better ways to diagnose and treat conditions, which could benefit patients like you.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WASHINGTON UNIVERSITY (nih funded) |
| Locations | 1 site (SAINT LOUIS, UNITED STATES) |
| Trial ID | NIH-11083076 on ClinicalTrials.gov |
What this research studies
This research focuses on exploring how genetic variations in somatic tissues can influence human health and disease. The project aims to create a comprehensive catalog of these variations by generating high-quality genomic DNA and RNA sequencing data. Patients may benefit from this research as it seeks to uncover new biological processes that could lead to improved diagnostics and treatments. The research will involve collaboration with various institutions to ensure efficient data management and analysis.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with conditions that may be influenced by somatic genetic variations.
Not a fit: Patients with purely hereditary conditions that do not involve somatic mutations may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding diseases linked to genetic variations, potentially improving patient outcomes.
How similar studies have performed: Previous research has shown promise in understanding somatic mosaicism, indicating that this approach could yield valuable insights.
Where this research is happening
SAINT LOUIS, UNITED STATES
- WASHINGTON UNIVERSITY — SAINT LOUIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WANG, TING — WASHINGTON UNIVERSITY
- Study coordinator: WANG, TING
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.