Understanding genetic variation in complex traits and diseases

Population genetic modeling of genetic variation for complex traits and diseases

NIH-funded research University of Chicago · NIH-10914161

This study is looking at how our genes and other factors work together to influence different traits and diseases, and it’s designed for anyone interested in understanding more about how our backgrounds can affect our health.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Chicago NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-10914161 on NIH RePORTER

What this research studies

This research focuses on the genetic complexity of various traits and diseases, exploring how both genetic and non-genetic factors contribute to their development. The team will develop advanced statistical methods to address challenges in measuring and interpreting genetic associations, particularly in relation to ancestry biases. By utilizing large biobank resources and modern genetic datasets, the research aims to enhance our understanding of the biological and evolutionary aspects of complex traits.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals with a family history of complex genetic diseases or those interested in understanding their genetic predispositions.

Not a fit: Patients with purely environmental or non-genetic conditions may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved genetic predictions and better understanding of disease risks, ultimately aiding in personalized medicine.

How similar studies have performed: Previous research has shown promise in using genetic modeling to understand complex traits, indicating that this approach could yield valuable insights.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions DiseaseDisorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.