Understanding genetic variation in complex traits and diseases
Official title: Population genetic modeling of genetic variation for complex traits and diseases
Funded at University of Chicago · NIH-10914161 · Data updated 2026-11-12
This study is looking at how our genes and other factors work together to influence different traits and diseases, and it’s designed for anyone interested in understanding more about how our backgrounds can affect our health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | September 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $392,592 |
| NIH project number | 5R35GM151257-02 |
| Project ID | NIH-10914161 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with a family history of complex genetic diseases or those interested in understanding their genetic predispositions.
✕Less likely to help
Patients with purely environmental or non-genetic conditions may not receive direct benefits from this research.
What this research studies
This research focuses on the genetic complexity of various traits and diseases, exploring how both genetic and non-genetic factors contribute to their development. The team will develop advanced statistical methods to address challenges in measuring and interpreting genetic associations, particularly in relation to ancestry biases. By utilizing large biobank resources and modern genetic datasets, the research aims to enhance our understanding of the biological and evolutionary aspects of complex traits.
Why it matters
Potential benefit: If successful, this research could lead to improved genetic predictions and better understanding of disease risks, ultimately aiding in personalized medicine.
How similar studies have gone: Previous research has shown promise in using genetic modeling to understand complex traits, indicating that this approach could yield valuable insights.
Where this research is happening
-
University of Chicago
Chicago, United States Active
Researchers
- Principal investigator: Berg, Jeremy Jackson — University of Chicago
- Study coordinator: Berg, Jeremy Jackson
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.