Understanding genetic variants through genomic data
GENOMIC INDEXING OF COMMON FUND DATASETS
This study is working to make it easier for doctors and researchers to understand the role of genetic changes that don’t directly code for proteins, which could help patients get better, more personalized treatment based on their unique genetics.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10223726 on NIH RePORTER |
What this research studies
This research focuses on improving the accessibility and interpretation of genetic variants, particularly those that are non-coding, which make up 99% of variants revealed by whole genome sequencing (WGS). By utilizing high-volume genomic datasets generated by various Common Fund projects, the research aims to provide detailed insights into how specific regulatory variants affect gene expression and function. The project will enhance the sharing of information about these variants, making it easier for researchers and clinicians to understand their implications in health and disease. Patients may benefit from improved genetic interpretation that could inform personalized treatment options.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals undergoing genetic testing or those with known genetic variants, particularly non-coding variants.
Not a fit: Patients with no genetic variants or those not undergoing genetic testing may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and interpretation of genetic variants, ultimately improving personalized medicine approaches for patients.
How similar studies have performed: Previous research has shown success in utilizing genomic data to interpret genetic variants, indicating that this approach has potential for meaningful advancements.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Milosavljevic, Aleksandar — Baylor College of Medicine
- Study coordinator: Milosavljevic, Aleksandar
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.