Understanding genetic traits in Holstein cattle
Genomic discovery and prediction for quantitative traits with complex genetic mechanisms
['FUNDING_R01'] · UNIVERSITY OF MINNESOTA · NIH-10767869
This study is looking at how different genes work together in Holstein cows to affect important traits like fertility, health, and how long they live, so that farmers can use this information to breed better cattle.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF MINNESOTA (nih funded) |
| Locations | 1 site (MINNEAPOLIS, UNITED STATES) |
| Trial ID | NIH-10767869 on ClinicalTrials.gov |
What this research studies
This research investigates the complex genetic mechanisms that influence various traits in Holstein cattle, focusing on gene interactions known as epistasis. By analyzing a large dataset of over 3.8 million genotyped cows, the project aims to uncover how multiple genetic factors contribute to traits such as fertility, health, and longevity. The study employs advanced computational methods to identify these interactions, which can lead to better breeding strategies and improved cattle production. Patients, in this case, are stakeholders in the cattle industry who may benefit from enhanced genetic insights.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include cattle breeders, farmers, and agricultural researchers focused on improving cattle genetics.
Not a fit: Patients who may not receive benefit from this research include those not involved in the cattle industry or those focused on non-bovine agricultural practices.
Why it matters
Potential benefit: If successful, this research could lead to improved breeding practices and healthier cattle, ultimately benefiting the dairy and beef industries.
How similar studies have performed: Other research has shown success in understanding genetic traits through similar genomic approaches, particularly in livestock genetics.
Where this research is happening
MINNEAPOLIS, UNITED STATES
- UNIVERSITY OF MINNESOTA — MINNEAPOLIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DA, YANG — UNIVERSITY OF MINNESOTA
- Study coordinator: DA, YANG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.