Understanding genetic signals related to psoriasis in diverse populations
Official title: Integrative and trans-ethnic study to understand psoriasis associated signals
Funded at University of Michigan at Ann Arbor · NIH-10932857 · Data updated 2026-11-12
This study is looking at the genes that might play a role in psoriasis, especially in people of African descent, to help find better treatments that work for different groups of people.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | September 21, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $366,372 |
| NIH project number | 5R01AR080662-02 |
| Project ID | NIH-10932857 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with psoriasis, especially those of African descent.
✕Less likely to help
Patients with psoriasis who do not have African ancestry may not receive direct benefits from this research.
What this research studies
This research investigates the genetic and genomic factors associated with psoriasis, a chronic skin disease, particularly focusing on individuals of African ancestry. By utilizing advanced technologies like ATAC sequencing, the study aims to identify and understand the genetic variations that contribute to psoriasis pathology. The research will analyze data from diverse populations to uncover how these genetic signals differ across ethnic groups, which could lead to more effective treatments tailored to specific populations.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for psoriasis, particularly for African American patients who are often underrepresented in genetic studies.
How similar studies have gone: Previous research has shown success in identifying genetic factors in psoriasis, but this study's focus on a multi-ethnic approach is relatively novel.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Tsoi, Lam Cheung — University of Michigan at Ann Arbor
- Study coordinator: Tsoi, Lam Cheung
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.