Understanding genetic risks for Alzheimer’s disease in diverse populations
Genomic Characterization of Alzheimer Disease Risk in Admixed Populations with Native American and Southern European Genetic Ancestry
This study is looking at how genetics might affect the risk of Alzheimer’s disease in people with Native American and Southern European backgrounds, hoping to find important clues that could help everyone understand the condition better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project ID | NIH-11009956 on NIH RePORTER |
What this research studies
This research investigates the genetic factors that contribute to Alzheimer’s disease (AD) risk in populations with Native American and Southern European ancestry. By analyzing genetic data from these underrepresented groups, the study aims to identify specific risk and protective factors associated with Alzheimer’s. The approach includes comparing genetic information from diverse populations to better understand how ancestry influences AD risk. This research seeks to fill gaps in knowledge that have primarily focused on non-Hispanic White populations.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with Native American or Southern European ancestry who may be at risk for Alzheimer’s disease.
Not a fit: Patients without any genetic ties to Native American or Southern European ancestry may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved risk assessment and targeted prevention strategies for Alzheimer’s disease in diverse populations.
How similar studies have performed: While genetic studies of Alzheimer’s have been conducted, this research is novel in its focus on admixed populations and the specific ancestries involved.
Where this research is happening
Coral Gables, United States
- University of Miami School of Medicine — Coral Gables, United States (Active)
Researchers
- Principal investigator: Pericak-Vance, Margaret a. — University of Miami School of Medicine
- Study coordinator: Pericak-Vance, Margaret a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.