Understanding genetic relationships to improve disease treatment
Official title: A genome-wide genealogical framework for statistical and population genetic analysis
Funded at University of Southern California · NIH-10914862 · Data updated 2026-11-12
This study is looking at how family connections can help us understand complex diseases better, especially for diverse groups like African Americans and Asians, so that we can create more personalized and effective treatments based on your genetic background.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project start | September 1, 2023 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $519,955 |
| NIH project number | 5R01HG012605-02 |
| Project ID | NIH-10914862 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals from African American and Asian populations who are interested in understanding their genetic predispositions to certain diseases.
✕Less likely to help
Patients who do not belong to the targeted populations or those with conditions that are not influenced by genetic factors may not receive benefits from this research.
What this research studies
This research investigates how genetic relationships among individuals can enhance our understanding of complex diseases. It aims to develop new methods that account for the genealogical connections between individuals, particularly in diverse populations like African Americans and Asians. By utilizing advanced statistical models, the research seeks to improve the accuracy of genetic data analysis, which can lead to better insights into disease heritability and treatment options. Patients may benefit from more tailored and effective medical interventions based on their genetic backgrounds.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for complex diseases by providing insights into the genetic factors that contribute to these conditions.
How similar studies have gone: Previous research has shown promise in using genealogical frameworks to analyze genetic data, indicating that this approach could yield significant advancements in understanding complex traits.
Where this research is happening
-
University of Southern California
Los Angeles, United States Active
Researchers
- Principal investigator: Chiang, Charleston — University of Southern California
- Study coordinator: Chiang, Charleston
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.