Understanding genetic mutations in breast cancer among African American women
Somatic Mutations and Their Etiological Determinants for Breast Cancer in African American Women
This study is looking at the genetic changes in breast cancer among African American women to better understand why they often face more aggressive forms of the disease, with the hope of finding new insights that can help improve their care.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Roswell Park Cancer Institute Corp NIH-funded |
| Lab location | 1 site (Buffalo, United States) |
| Project ID | NIH-10558682 on NIH RePORTER |
What this research studies
This research investigates the genetic mutations associated with breast cancer specifically in African American women, who experience higher rates of aggressive forms of the disease. By analyzing tumor samples from a large dataset, the study aims to identify unique mutational patterns that may differ from those found in European populations. The researchers will explore how various environmental and genetic factors contribute to these mutations, potentially revealing new insights into breast cancer biology. This work seeks to address significant health disparities and improve understanding of breast cancer in this population.
Who could benefit from this research
Good fit: Ideal candidates for this research are African American women diagnosed with breast cancer, particularly those with triple-negative breast cancer.
Not a fit: Patients who do not have breast cancer or those from non-African American backgrounds may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective prevention and treatment strategies tailored specifically for African American women with breast cancer.
How similar studies have performed: Previous research has shown success in identifying unique genetic mutations in other cancer types among diverse populations, suggesting potential for similar breakthroughs in this study.
Where this research is happening
Buffalo, United States
- Roswell Park Cancer Institute Corp — Buffalo, United States (Active)
Researchers
- Principal investigator: Yao, Song — Roswell Park Cancer Institute Corp
- Study coordinator: Yao, Song
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.