Understanding genetic heart muscle diseases
Official title: Experimental and Computational Studies in Genetic Cardiomyopathies
Funded at University of Washington · NIH-11066524 · Data updated 2026-11-12
This study is looking at how changes in your genes can affect heart muscle function in people with conditions like hypertrophic and dilated cardiomyopathy, so we can better understand how to tailor treatments just for you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | May 1, 2022 |
| Project end | April 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $674,216 |
| NIH project number | 5R01HL157169-04 |
| Project ID | NIH-11066524 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with hypertrophic or dilated cardiomyopathy, particularly those with known genetic variants.
✕Less likely to help
Patients without genetic cardiomyopathies or those whose conditions are unrelated to genetic factors may not benefit from this research.
What this research studies
This research investigates genetic cardiomyopathies, such as hypertrophic and dilated cardiomyopathy, by utilizing advanced experimental and computational methods. The study aims to analyze how genetic variations affect the function of heart muscle cells, which can lead to these conditions. By employing high-throughput assays and data analytics, the research seeks to classify genetic variants and predict how patients might respond to different treatments. This approach aims to enhance precision medicine strategies for individuals with these heart diseases.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment options for patients with genetic heart muscle diseases.
How similar studies have gone: Other research has shown promise in using computational and experimental approaches to understand genetic cardiomyopathies, indicating that this methodology has potential for success.
Where this research is happening
-
University of Washington
Seattle, United States Active
Researchers
- Principal investigator: Moussavi-Harami, Farid — University of Washington
- Study coordinator: Moussavi-Harami, Farid
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.