Understanding genetic factors that influence prostate cancer development

Germline Determinants of Prostate Cancer Evolution

['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-11056737

This study is looking at how your genes from your parents might influence the way prostate cancer develops and how aggressive it can be, with the hope of finding clues that could help doctors tailor treatments just for you.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded)
Locations1 site (LOS ANGELES, UNITED STATES)
Trial IDNIH-11056737 on ClinicalTrials.gov

What this research studies

This research investigates how genetic factors inherited from parents may affect the development and aggressiveness of prostate cancer in men. By analyzing the genetic makeup of individuals and comparing it with their cancer characteristics, the study aims to identify specific genetic markers that could predict the risk and severity of prostate cancer. The research will utilize advanced genomic techniques and data analysis to uncover these relationships, potentially leading to more personalized treatment approaches for patients. The findings could help refine current screening and treatment strategies for prostate cancer.

Who could benefit from this research

Good fit: Ideal candidates for this research include men of various ancestries, particularly those with a family history of prostate cancer or those diagnosed with localized prostate cancer.

Not a fit: Patients with advanced metastatic prostate cancer or those without a genetic predisposition to prostate cancer may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved risk assessment and treatment strategies for prostate cancer, ultimately enhancing patient outcomes.

How similar studies have performed: Previous research has shown promising results in understanding genetic influences on prostate cancer, indicating that this approach has potential for significant advancements.

Where this research is happening

LOS ANGELES, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.