Understanding genetic factors that increase the risk of skin cancer.
The Role of Genetic Risk Factors in Keratinocyte Carcinoma Susceptibility
This study is looking at how your genes and things like sun exposure and smoking might affect your risk of getting common skin cancers, like basal cell and squamous cell carcinoma, to help find better ways to prevent and treat these conditions for people who are more at risk.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Kaiser Foundation Research Institute NIH-funded |
| Lab location | 1 site (Oakland, UNITED STATES) |
| Project ID | NIH-11035181 on NIH RePORTER |
What this research studies
This research investigates the genetic risk factors associated with keratinocyte carcinoma, which includes basal cell carcinoma and squamous cell carcinoma, the most common types of skin cancer in the U.S. The study aims to identify specific genetic loci that contribute to the susceptibility of these cancers and how environmental factors like sun exposure and smoking may influence these genetic risks. By analyzing data from patients, the research seeks to develop a risk prediction model that can help identify individuals at higher risk for these skin cancers. This could lead to more personalized prevention strategies and treatment options for patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults with a family history of skin cancer or those who have experienced significant sun exposure.
Not a fit: Patients with skin cancers unrelated to genetic factors or those who do not have a history of significant sun exposure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved risk assessment and targeted prevention strategies for individuals at high risk of skin cancer.
How similar studies have performed: Previous research has shown success in identifying genetic risk factors for other types of cancers, suggesting that this approach may yield valuable insights for keratinocyte carcinoma as well.
Where this research is happening
Oakland, UNITED STATES
- Kaiser Foundation Research Institute — Oakland, United States (Active)
Researchers
- Principal investigator: Choquet, Helene — Kaiser Foundation Research Institute
- Study coordinator: Choquet, Helene
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.