Understanding genetic factors that help some people cope with chronic obstructive pulmonary disease (COPD)
Official title: Genetic and Transcriptomic Resilience in Chronic Obstructive Pulmonary Disease
Funded at Upstate Medical University · NIH-11009987 · Data updated 2026-11-12
This study is looking at how your genes and other biological factors might help some people with COPD feel better and cope with their condition, so we can find ways to predict who might do well and improve care for everyone with COPD.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Upstate Medical University NIH-funded |
| Lab location | 1 site (Syracuse, United States) |
| Project start | January 15, 2024 |
| Project end | December 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $200,364 |
| NIH project number | 5K08HL168205-02 |
| Project ID | NIH-11009987 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with chronic obstructive pulmonary disease who are interested in understanding the genetic factors influencing their condition.
✕Less likely to help
Patients without a diagnosis of chronic obstructive pulmonary disease or those with other unrelated respiratory conditions may not benefit from this research.
What this research studies
This research investigates how certain genetic and transcriptomic factors contribute to resilience in patients with chronic obstructive pulmonary disease (COPD). By analyzing existing data from well-characterized studies, the research aims to identify genetic variations that are linked to better outcomes in COPD patients. The study will also explore clinical and imaging features that characterize resilience and develop predictive models based on blood gene-expression data. This approach combines advanced genetic analysis with machine learning techniques to enhance our understanding of COPD.
Why it matters
Potential benefit: If successful, this research could lead to personalized treatment strategies that improve the quality of life for COPD patients.
How similar studies have gone: Previous research has shown promise in using genetic and transcriptomic analyses to understand respiratory diseases, indicating that this approach could yield valuable insights.
Where this research is happening
-
Upstate Medical University
Syracuse, United States Active
Researchers
- Principal investigator: Ghosh, Auyon — Upstate Medical University
- Study coordinator: Ghosh, Auyon
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.