Understanding genetic factors in Lewy Body dementia
-Omics driven network analysis in Lewy Body dementia
This study is looking at how our genes might affect Lewy Body dementia, helping us understand why it happens and how it progresses, which could lead to new ways to treat it.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Jacksonville NIH-funded |
| Lab location | 1 site (Jacksonville, United States) |
| Project ID | NIH-10686897 on NIH RePORTER |
What this research studies
This research investigates the genetic and molecular factors that contribute to Lewy Body dementia (LBD) by analyzing large datasets derived from genomic studies. The team will explore how specific genetic variants influence the progression of the disease and the associated neuronal cell loss. By utilizing advanced techniques like whole-genome sequencing and RNA sequencing, the study aims to uncover the underlying biological pathways that differentiate LBD from other forms of dementia. This comprehensive approach may lead to better understanding and potential new targets for treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research include older adults diagnosed with Lewy Body dementia or those exhibiting symptoms related to this condition.
Not a fit: Patients with other forms of dementia, such as frontotemporal dementia or vascular dementia, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and targeted therapies for patients with Lewy Body dementia.
How similar studies have performed: Previous research has shown promise in using genomic approaches to understand dementia, suggesting that this methodology could yield valuable insights.
Where this research is happening
Jacksonville, United States
- Mayo Clinic Jacksonville — Jacksonville, United States (Active)
Researchers
- Principal investigator: Ross, Owen a — Mayo Clinic Jacksonville
- Study coordinator: Ross, Owen a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.