Understanding genetic factors in epilepsy through advanced DNA sequencing.
Project-004
This study is looking at how new DNA testing can help us understand the genetic causes of epilepsy, especially the confusing genetic results that come from tests, so we can make better decisions for people living with this condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-10873154 on NIH RePORTER |
What this research studies
This research focuses on the rapid advancements in DNA sequencing technology to identify genetic factors associated with epilepsy. It aims to address the challenge of interpreting genetic variants of uncertain significance that arise from clinical testing. By collaborating across multiple institutions, the project will develop a comprehensive platform to analyze these genetic variants and their implications for patients. The goal is to enhance understanding of the biological mechanisms underlying epilepsy and improve clinical decision-making for affected individuals.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with early-onset, familial, or refractory epilepsy who have undergone genetic testing.
Not a fit: Patients without a diagnosis of epilepsy or those who have not undergone genetic testing may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and personalized treatment options for patients with epilepsy.
How similar studies have performed: Previous research has shown promise in using advanced genetic sequencing to uncover new insights into epilepsy, indicating that this approach has potential for significant breakthroughs.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Isom, Lori L. — University of Michigan at Ann Arbor
- Study coordinator: Isom, Lori L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.