Understanding genetic factors in autoimmune diseases
Methods and tools to integrate multi-omics datasets to understand preclinical autoimmune and immune-mediated diseases
['FUNDING_U01'] · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · NIH-11132900
This study is looking at how our genes might play a role in the early signs of autoimmune diseases, so we can find better ways to spot these conditions early and help people who are at risk.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | PENNSYLVANIA STATE UNIV HERSHEY MED CTR (nih funded) |
| Locations | 1 site (HERSHEY, UNITED STATES) |
| Trial ID | NIH-11132900 on ClinicalTrials.gov |
What this research studies
This research focuses on identifying genetic factors that contribute to the early stages of autoimmune and immune-mediated diseases. By developing new methods and software tools, the project aims to analyze multi-omics datasets to detect genetic associations and understand how these factors influence the progression from preclinical symptoms to full-blown disease. This approach will help in recognizing early signs of autoimmune conditions, which can be challenging due to non-specific symptoms. The findings could lead to improved diagnostic techniques and targeted interventions for patients at risk.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing early or preclinical symptoms of autoimmune diseases such as lupus, psoriasis, or Sjogren's disease.
Not a fit: Patients with well-established autoimmune diseases who are already receiving treatment may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate diagnoses of autoimmune diseases, potentially improving treatment outcomes.
How similar studies have performed: Previous research has shown promise in using genetic analysis to understand autoimmune diseases, indicating that this approach could yield valuable insights.
Where this research is happening
HERSHEY, UNITED STATES
- PENNSYLVANIA STATE UNIV HERSHEY MED CTR — HERSHEY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LIU, DAJIANG — PENNSYLVANIA STATE UNIV HERSHEY MED CTR
- Study coordinator: LIU, DAJIANG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.