Understanding genetic factors in Alzheimer's disease across different ethnic groups
Project 2: Multi-Ethnic Analysis for Alzheimer Disease
This study is looking at how genetics might affect the risk of Alzheimer's disease, especially in African American and Hispanic/Latinx communities, to help create better prevention and treatment options that fit their unique backgrounds.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project ID | NIH-10892914 on NIH RePORTER |
What this research studies
This research investigates the genetic components of Alzheimer's disease (AD) by focusing on diverse populations, particularly African Americans and Hispanic/Latinx individuals, who are at higher risk for the disease. The study aims to identify unique genetic alleles and modifiers that may influence AD risk in these groups, which have been underrepresented in previous research primarily focused on individuals of European descent. By recruiting diverse cohorts and utilizing advanced genetic mapping techniques, the research seeks to enhance our understanding of how ancestry impacts Alzheimer's disease risk and to develop better risk models. Patients participating in this research may contribute to groundbreaking findings that could lead to more effective prevention and treatment strategies tailored to their specific genetic backgrounds.
Who could benefit from this research
Good fit: Ideal candidates for participation include African American and Hispanic/Latinx individuals who may be at risk for Alzheimer's disease.
Not a fit: Patients of European descent may not receive direct benefits from this research as it focuses on genetic factors specific to African American and Hispanic/Latinx populations.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of Alzheimer's disease risk in diverse populations.
How similar studies have performed: Previous research has shown success in identifying genetic risk factors for Alzheimer's disease in various populations, but this study aims to explore novel aspects that have not been extensively tested.
Where this research is happening
Coral Gables, United States
- University of Miami School of Medicine — Coral Gables, United States (Active)
Researchers
- Principal investigator: Tosto, Giuseppe — University of Miami School of Medicine
- Study coordinator: Tosto, Giuseppe
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.