Understanding genetic factors in age-related vision loss
Optimizing Models of Non-Coding Genetic Risk in Age-Related Macular Degeneration
This study is looking at how certain genetic factors might increase the risk of age-related macular degeneration (AMD), with the goal of finding better ways to understand and treat this eye condition that affects vision.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Seattle Children's Hospital NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11046616 on NIH RePORTER |
What this research studies
This research investigates how specific non-coding genetic elements contribute to the risk of developing age-related macular degeneration (AMD). By optimizing and validating experimental models, the researchers aim to directly test the function of these genetic elements in both human cells and mouse models. This approach will help clarify the genetic mechanisms behind AMD, potentially leading to better understanding and treatment options for this condition. Patients may benefit from insights gained into the genetic factors that influence their risk of vision loss.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals at risk for age-related macular degeneration, particularly those with a family history of the condition.
Not a fit: Patients with other forms of vision loss unrelated to age-related macular degeneration may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing or treating age-related macular degeneration.
How similar studies have performed: Previous research has shown success in understanding genetic contributions to other conditions, suggesting potential for breakthroughs in this area as well.
Where this research is happening
Seattle, United States
- Seattle Children's Hospital — Seattle, United States (Active)
Researchers
- Principal investigator: Cherry, Timothy Joel — Seattle Children's Hospital
- Study coordinator: Cherry, Timothy Joel
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.