Understanding genetic factors in a rare form of dementia
Core D: Data
This study is looking at the genes that might increase the risk of Progressive Supranuclear Palsy and a specific type of frontotemporal dementia, to help us understand the disease better and support future research, so it’s for anyone interested in these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-11260089 on NIH RePORTER |
What this research studies
This research focuses on identifying and analyzing the genetic risk factors associated with Progressive Supranuclear Palsy and FTD-Tau, a rare inherited form of frontotemporal dementia. By utilizing advanced genomic and multi-omic techniques, the project aims to generate a comprehensive dataset that includes various biological data types, such as transcriptomics and proteomics. This data will be crucial for understanding how genetic variations impact the disease and for facilitating further research in the field. The Data Core will play a vital role in managing and sharing this information with the broader scientific community.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Progressive Supranuclear Palsy or FTD-Tau, particularly those with known mutations in the MAPT gene.
Not a fit: Patients with other forms of dementia or neurological disorders unrelated to the genetic factors being studied may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and potential new treatments for patients with Progressive Supranuclear Palsy and related dementias.
How similar studies have performed: Previous research has shown promise in using genomic approaches to understand neurodegenerative diseases, indicating that this methodology could yield valuable insights.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Chang, Timothy S — University of California Los Angeles
- Study coordinator: Chang, Timothy S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.