Understanding genetic factors contributing to ischemic stroke in people of African ancestry
CIDR: GENOTYPING SERVICES USING GWAS ILLUMINA H3AFRICA ARRAY FOR NINDS (OWOLABI)
This study is looking at the genes that might cause ischemic stroke in people of African descent, hoping to find new information that can help create better treatments and prevention strategies for stroke in this community.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10948250 on NIH RePORTER |
What this research studies
This research focuses on identifying and characterizing genetic variants that contribute to ischemic stroke, particularly in individuals of African descent. By analyzing genetic data using the Illumina H3Africa array, the study aims to uncover novel genetic factors that have not been previously validated in stroke research. The approach involves leveraging existing NIH-funded initiatives to gather comprehensive genetic information, which will help in understanding the unique biological processes leading to stroke in this population. The ultimate goal is to develop tailored interventions that can effectively reduce the burden of stroke among individuals of African ancestry.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals of African ancestry who may be at risk for ischemic stroke.
Not a fit: Patients who do not have a genetic predisposition to ischemic stroke or those outside of the African ancestry demographic may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to personalized treatment strategies that significantly reduce the risk of ischemic stroke in patients of African descent.
How similar studies have performed: Previous research has shown success in identifying genetic factors associated with stroke in other populations, but this study aims to fill a critical gap by focusing on individuals of African ancestry, making it a novel approach.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Doheny, Kimberly F — Johns Hopkins University
- Study coordinator: Doheny, Kimberly F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.