Understanding genetic factors behind addictive behaviors in rodents

Characterization of Tandem Repeat and Structural Variants Contributing to Addictive Behaviors in Mice and Rats

NIH-funded research University of California, San Diego · NIH-11046648

This study is looking at how certain genetic differences in mice and rats might lead to addictive behaviors, which could help us understand addiction better and find new ways to treat it.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego NIH-funded
Lab location1 site (La Jolla, United States)
Project IDNIH-11046648 on NIH RePORTER

What this research studies

This research investigates the genetic variations that contribute to addictive behaviors in mice and rats. By focusing on structural variants and tandem repeats, which are often overlooked in traditional genetic studies, the project aims to identify the causal genes linked to addiction. The researchers will utilize advanced genetic analysis techniques to create a comprehensive resource that will help in understanding how these genetic factors influence behavior. This work could provide insights into the biological underpinnings of addiction, potentially leading to better treatment strategies.

Who could benefit from this research

Good fit: Ideal candidates for benefiting from this research are individuals with a history of addictive behaviors or disorders.

Not a fit: Patients who do not have any history of addiction or related behavioral issues may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment options for addiction in humans.

How similar studies have performed: Previous research has shown promise in understanding genetic contributions to addiction, but this approach focusing on structural variants and tandem repeats is relatively novel.

Where this research is happening

La Jolla, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions addictive disorderautism spectral disorderautism spectrum disorderAutistic Disorderautistic spectrum disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.