Understanding genetic factors and nerve degeneration in diabetic eye disease
Diabetic Retinopathy: Genetics and Neurodegeneration (MSN246458)
This study is looking into how genetics and long-term high blood sugar levels affect eye health in people with diabetes, aiming to better understand and spot the different ways diabetic retinopathy can develop, so we can help prevent vision loss.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-10838483 on NIH RePORTER |
What this research studies
This research investigates the genetic factors and neurodegeneration associated with diabetic retinopathy, a leading cause of vision loss in adults with diabetes. It aims to explore how hyperglycemia and the duration of diabetes contribute to the development of this condition, while also examining the role of genetic predisposition and new imaging techniques to identify different manifestations of diabetic retinal disease. By utilizing advanced imaging and data analysis, the study seeks to uncover the complexities of diabetic retinal neurodegeneration, which is often overlooked in current clinical practices.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who have been diagnosed with diabetes and are at risk for diabetic retinopathy.
Not a fit: Patients who do not have diabetes or those with advanced diabetic eye disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of diabetic eye diseases, potentially reducing vision loss in patients with diabetes.
How similar studies have performed: Previous research has shown promise in understanding the genetic and neurodegenerative aspects of diabetic eye diseases, but this specific approach is relatively novel.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Channa, Roomasa — University of Wisconsin-Madison
- Study coordinator: Channa, Roomasa
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.