Understanding genetic factors affecting outcomes in congenital heart disease
Identifying and applying genetic variation relevant to clinical outcomes for individuals with congenital heart disease
This study is looking at how differences in our genes can affect the health and development of people with congenital heart disease, so we can better understand their needs and improve their care and treatment.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10890819 on NIH RePORTER |
What this research studies
This research investigates how genetic variations influence the clinical outcomes of individuals with congenital heart disease (CHD). By analyzing genetic data, the study aims to identify specific genes that may affect not only heart function but also cognitive and behavioral development. The findings will be used to enhance clinical care and design more effective treatment trials for CHD patients. Ultimately, the goal is to improve patient outcomes by anticipating and preventing complications associated with CHD.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with congenital heart disease, particularly those experiencing cognitive or behavioral issues.
Not a fit: Patients with congenital heart disease who do not have any genetic variations affecting their condition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatments for patients with congenital heart disease.
How similar studies have performed: Previous research has shown promise in using genetic information to improve treatment outcomes in other conditions, suggesting potential success for this approach in congenital heart disease.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Shen, Yufeng — Columbia University Health Sciences
- Study coordinator: Shen, Yufeng
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.