Understanding genetic factors affecting heart rhythm variations
Identifying Cis-Regulatory Variants, Genes, and Regulatory Networks Underlying QT Interval Variation
This study is looking at how certain genes affect the QT interval, which is important for heart rhythm and can help identify the risk of heart problems, so that patients can learn more about their own heart health and get tailored treatment options.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Sci Ctr Houston NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11064081 on NIH RePORTER |
What this research studies
This research investigates the genetic variants that influence the QT interval, a measure of heart rhythm that can indicate the risk of serious heart conditions. By analyzing both common and rare genetic mutations, the study aims to identify the genes and regulatory networks involved in QT interval variation. Patients may benefit from insights into their genetic predisposition to cardiac arrhythmias, which could lead to personalized treatment strategies. The research employs advanced genetic analysis techniques to uncover the underlying mechanisms of these variations.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a family history of cardiac arrhythmias or those who have experienced unexplained heart rhythm issues.
Not a fit: Patients without any history of cardiac arrhythmias or related genetic conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved risk assessment and personalized treatment options for patients at risk of cardiac arrhythmias.
How similar studies have performed: Previous genetic studies have successfully identified variants associated with heart conditions, suggesting that this approach has the potential for meaningful discoveries.
Where this research is happening
Houston, United States
- University of Texas Hlth Sci Ctr Houston — Houston, United States (Active)
Researchers
- Principal investigator: Kapoor, Ashish — University of Texas Hlth Sci Ctr Houston
- Study coordinator: Kapoor, Ashish
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.