Understanding genetic factors affecting blood sugar levels in Mexican Americans
Genetic and Epidemiological Predictors of Glucose Homeostasis Measures
This study is looking at how our genes and biology affect how well our bodies handle insulin and blood sugar, especially for Mexican Americans who are more likely to develop type 2 diabetes, to help find ways to better manage and prevent the condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wake Forest University Health Sciences NIH-funded |
| Lab location | 1 site (Winston-Salem, United States) |
| Project ID | NIH-10557133 on NIH RePORTER |
What this research studies
This research investigates how genetic and biological factors influence insulin sensitivity and secretion, which are critical for managing blood sugar levels and preventing type 2 diabetes (T2D). By focusing on Mexican Americans, a population at high risk for T2D, the study aims to identify genetic variations that contribute to glucose homeostasis. The research employs advanced methodologies, including genome-wide association studies and metabolomics, to uncover the biological mechanisms behind these traits. Participants may contribute to a better understanding of how genetics affects diabetes risk and treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are Mexican Americans who are at risk for type 2 diabetes or have a family history of the condition.
Not a fit: Patients who do not identify as Mexican American or who do not have risk factors for type 2 diabetes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing and managing type 2 diabetes in high-risk populations.
How similar studies have performed: Previous research has successfully identified genetic factors related to diabetes, making this approach promising for further advancements.
Where this research is happening
Winston-Salem, United States
- Wake Forest University Health Sciences — Winston-Salem, United States (Active)
Researchers
- Principal investigator: Allred, Nicholette D. — Wake Forest University Health Sciences
- Study coordinator: Allred, Nicholette D.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.