Understanding genetic diversity in mouse populations
Population genomics in laboratory and outbred mouse populations
['FUNDING_OTHER'] · JACKSON LABORATORY · NIH-11011789
This study looks at how different genes in mouse populations change over time due to natural processes, which could help us understand genetic variations linked to diseases that might also affect humans.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JACKSON LABORATORY (nih funded) |
| Locations | 1 site (BAR HARBOR, UNITED STATES) |
| Trial ID | NIH-11011789 on ClinicalTrials.gov |
What this research studies
This research investigates how genetic diversity within mouse populations is shaped by various evolutionary processes such as mutation and natural selection. By utilizing advanced genomic techniques, the study aims to uncover the mechanisms behind genetic variations that may contribute to diseases. The research will focus on specific genomic regions that are rich in repetitive sequences, which are crucial for chromosome stability and fertility. Through the use of diverse mouse strains and extensive genomic data, the project seeks to provide insights that could be relevant to human health.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals with a family history of genetic disorders or those interested in the genetic basis of diseases.
Not a fit: Patients with no genetic predisposition to diseases or those not interested in genetic research may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of genetic factors that contribute to disease risk in humans.
How similar studies have performed: Other research has shown success in using mouse models to study genetic diversity and its implications for human health, indicating that this approach is well-established.
Where this research is happening
BAR HARBOR, UNITED STATES
- JACKSON LABORATORY — BAR HARBOR, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DUMONT, BETHANY L — JACKSON LABORATORY
- Study coordinator: DUMONT, BETHANY L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancers