Understanding Genetic Differences in Primates Relevant to Human Health
Characterizing the full spectrum of genomic variation in biomedically-relevant primates
This project aims to understand the full range of genetic differences in primates that are important for biomedical research, helping us learn more about human health and disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Arizona State University-Tempe Campus NIH-funded |
| Lab location | 1 site (Scottsdale, United States) |
| Project ID | NIH-11090512 on NIH RePORTER |
What this research studies
Our genes play a big role in our health, and small changes in our DNA can lead to various conditions. This project looks beyond simple gene changes to focus on larger "structural variants" – pieces of DNA that are inserted, deleted, or rearranged. These larger changes are often overlooked but can significantly impact how our genes work and contribute to complex health issues. By studying these genetic differences in primates that are similar to humans, we hope to uncover new insights into human diseases.
Who could benefit from this research
Good fit: This foundational genetic research does not directly involve patient participation, but future studies building on these findings may seek individuals with complex genetic conditions.
Not a fit: Patients seeking immediate treatment or direct clinical intervention will not find direct benefit from this basic science project.
Why it matters
Potential benefit: This work could help us better understand the genetic causes of complex human diseases and conditions, potentially leading to new ways to prevent or treat them in the future.
How similar studies have performed: While some human structural variant catalogs exist, comprehensive datasets for non-human primates are limited, making this a novel and foundational approach in this specific area.
Where this research is happening
Scottsdale, United States
- Arizona State University-Tempe Campus — Scottsdale, United States (Active)
Researchers
- Principal investigator: Pfeifer, Susanne P — Arizona State University-Tempe Campus
- Study coordinator: Pfeifer, Susanne P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.