Understanding genetic differences in health risks among diverse populations
An evolutionary framework to elucidate and interpret the genetic architecture of complex traits in diverse populations
This study is looking at how our genes and the environment we live in affect health differences between different groups of people, with the goal of helping patients understand and manage conditions like obesity and diabetes better based on their unique backgrounds.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project ID | NIH-11089588 on NIH RePORTER |
What this research studies
This research investigates how both genetic and environmental factors contribute to health disparities among different populations. By integrating evolutionary biology with genetic epidemiology, the project aims to uncover the genetic architecture of complex traits, such as obesity and diabetes, and how these traits vary across populations. The research will utilize data analysis and quantitative methods to explore the demographic and adaptive histories of human groups, ultimately aiming to improve personalized healthcare practices. Patients may benefit from insights that lead to better understanding and management of their health conditions based on their genetic backgrounds.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals from diverse ethnic backgrounds who may be at risk for complex health conditions like diabetes or obesity.
Not a fit: Patients who do not belong to diverse populations or those with conditions unrelated to the genetic traits being studied may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective healthcare strategies tailored to the genetic backgrounds of diverse populations.
How similar studies have performed: Previous research has shown promise in using evolutionary frameworks to understand genetic diversity and health disparities, indicating that this approach could yield valuable insights.
Where this research is happening
Los Angeles, UNITED STATES
- University of Southern California — Los Angeles, United States (Active)
Researchers
- Principal investigator: Chiang, Charleston — University of Southern California
- Study coordinator: Chiang, Charleston
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.