Understanding genetic communication for localized prostate cancer
Official title: Genetic Literacy and Patient-Caregiver Communication of Prognostic Genetic Technology for Localized Prostate Cancer
Funded at Mayo Clinic Arizona · NIH-10918068 · Data updated 2026-11-12
This study is looking at how men with localized prostate cancer and their caregivers talk about new genetic tests that can help with treatment choices, and it wants to see if educational videos can make these conversations easier for everyone, no matter their background.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Arizona NIH-funded |
| Lab location | 1 site (Scottsdale, United States) |
| Project start | September 1, 2022 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $168,264 |
| NIH project number | 5K01CA230193-05 |
| Project ID | NIH-10918068 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are men diagnosed with localized prostate cancer and their caregivers, particularly those from low-income or disadvantaged backgrounds.
✕Less likely to help
Patients with advanced prostate cancer or those who do not have caregivers involved in their treatment may not receive benefit from this research.
What this research studies
This research investigates how men with localized prostate cancer and their caregivers understand and communicate about new genetic technologies that can inform treatment decisions. It aims to explore the comprehension of prognostic genetic tests and the impact of educational videos on improving communication between patients and caregivers. By focusing on health disparities, the study seeks to ensure that all patients, regardless of education level or socioeconomic status, can benefit from advancements in genomic medicine.
Why it matters
Potential benefit: If successful, this research could enhance patient and caregiver understanding of genetic information, leading to better-informed treatment decisions for localized prostate cancer.
How similar studies have gone: Previous research has shown that educational interventions can improve patient understanding and communication regarding complex medical information, suggesting potential success for this approach.
Where this research is happening
-
Mayo Clinic Arizona
Scottsdale, United States Active
Researchers
- Principal investigator: Cobran, Ewan Kemar — Mayo Clinic Arizona
- Study coordinator: Cobran, Ewan Kemar
Related research
Other NIH-funded projects on the same topics.
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Deep learning MRI biomarkers to predict prostate cancer outcomes
A Yale-led project uses advanced MRI images and artificial intelligence to better predict how localized prostate cancer will behave in patients.
-
Exercise therapy to slow progression in localized prostate cancer on active surveillance
A study will test whether a structured home-based exercise program helps men with localized prostate cancer who are on active surveillance avoid moving to treatment or worsening, compared with usual care.
-
Biomarkers to identify aggressive prostate cancer early
A patient-friendly program to find and validate biomarkers in urine and tumor tissue that can flag aggressive prostate cancer early so men can get the right treatment sooner.
-
Home walking program for men on active surveillance for low-risk prostate cancer
This project sees if a year-long home treadmill walking program can change cancer-related markers and help men with low-grade prostate cancer on active surveillance avoid early treatment.
-
Precision pre-surgery therapy for high-risk PTEN-loss prostate cancer
This grant plans a targeted, pre-surgical treatment for men with high-risk localized prostate cancer who have PTEN loss, using intensified hormone therapy plus an AKT inhibitor before surgery.
-
Better tests to find aggressive early prostate cancer
This project develops urine and tissue biomarker tests and decision tools to help men with early prostate cancer learn whether their cancer is likely to be aggressive and needs treatment.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.