Understanding genetic changes in human populations over time
Population genetic methods to detect population structure and adaptation using modern and ancient genomic datasets
['FUNDING_R01'] · UNIVERSITY OF CHICAGO · NIH-11042830
This study looks at how our genes have changed over time because of where our ancestors lived and the challenges they faced, helping us understand how these changes might affect our health today.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CHICAGO (nih funded) |
| Locations | 1 site (CHICAGO, UNITED STATES) |
| Trial ID | NIH-11042830 on ClinicalTrials.gov |
What this research studies
This research investigates how genetic variations in human populations have evolved due to historical migrations and environmental pressures. By analyzing both modern and ancient genomic datasets, the study aims to identify adaptive genetic traits that may influence health and disease. The researchers will develop new analytical tools to better understand the demographic histories of populations and how these histories affect genetic diversity. This approach could lead to insights into the genetic basis of complex diseases and how they are influenced by our evolutionary past.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals from diverse ancestral backgrounds who may be affected by complex genetic diseases.
Not a fit: Patients with purely environmental or non-genetic conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of genetic factors that contribute to disease risk and inform personalized medicine approaches.
How similar studies have performed: Previous research has shown success in using genomic datasets to uncover population structures and adaptive traits, indicating that this approach is promising.
Where this research is happening
CHICAGO, UNITED STATES
- UNIVERSITY OF CHICAGO — CHICAGO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: STEINRUECKEN, MATTHIAS — UNIVERSITY OF CHICAGO
- Study coordinator: STEINRUECKEN, MATTHIAS
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.