Understanding genetic and non-genetic factors in heart disease risk
Integrating genomic and nongenomic risk for coronary artery disease
['FUNDING_CAREER'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-10888278
This study is looking at how your genes and other factors can affect your chances of getting coronary artery disease, so that doctors can give you personalized advice and treatment based on your unique situation.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MASSACHUSETTS GENERAL HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10888278 on ClinicalTrials.gov |
What this research studies
This research investigates how both genetic and non-genetic factors contribute to the risk of developing coronary artery disease (CAD). By integrating genomic data with other risk factors, the study aims to improve the understanding of CAD and enhance prevention strategies. Patients may benefit from personalized risk assessments and tailored treatment approaches based on their unique genetic profiles. The research is conducted by a team of experts at Massachusetts General Hospital and the Broad Institute, utilizing advanced methodologies in computational biology and predictive analytics.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for coronary artery disease, particularly those with a family history or other risk factors.
Not a fit: Patients who do not have any risk factors for coronary artery disease or those with established CAD may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective prevention and treatment strategies for coronary artery disease.
How similar studies have performed: Previous research has shown promise in integrating genetic and environmental factors to improve cardiovascular health outcomes, indicating that this approach could be beneficial.
Where this research is happening
BOSTON, UNITED STATES
- MASSACHUSETTS GENERAL HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FAHED, AKL C — MASSACHUSETTS GENERAL HOSPITAL
- Study coordinator: FAHED, AKL C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.