Understanding genetic and imaging factors in Alzheimer's disease risk and progression
Novel integrative imaging genetics analysis for Alzheimer's disease riskand progression
This study is looking at how our genes and brain scans might affect the risk and progression of Alzheimer's disease, and it’s for people who want to help us learn more about the condition so we can find better ways to manage or prevent it.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-11078674 on NIH RePORTER |
What this research studies
This research aims to explore the genetic factors and brain imaging characteristics that contribute to the risk and progression of Alzheimer's disease (AD). By utilizing advanced statistical models, the study will create detailed imaging profiles that reflect genetic influences on the disease. Patients may undergo imaging tests and genetic analysis to help identify how these elements interact and contribute to AD. The findings could lead to better understanding and potential new strategies for managing or preventing Alzheimer's.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a family history of Alzheimer's disease or those showing early signs of cognitive decline.
Not a fit: Patients who are not at risk for Alzheimer's disease or do not exhibit any cognitive symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for identifying individuals at risk for Alzheimer's disease and understanding its progression.
How similar studies have performed: Previous research has shown promise in using genetic and imaging data to understand Alzheimer's disease, indicating that this approach could yield valuable insights.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Zhao, Yize — Yale University
- Study coordinator: Zhao, Yize
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.