Understanding genetic and environmental factors in African Americans with inflammatory bowel disease
Official title: Integrative multi-omic risk assessment at diagnosis and during disease progression in African-Americans with Inflammatory bowel disease
Funded at Emory University · NIH-10885073 · Data updated 2026-11-12
This study is looking at how genes, gut bacteria, and lifestyle choices like diet and drinking can affect the progression of inflammatory bowel disease (IBD) in African Americans, with the hope of finding better ways to manage the condition for patients like you.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | September 30, 2022 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $550,668 |
| NIH project number | 5U01DK134191-03 |
| Project ID | NIH-10885073 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are African American individuals diagnosed with inflammatory bowel disease.
✕Less likely to help
Patients who are not of African descent or those without a diagnosis of inflammatory bowel disease may not benefit from this research.
What this research studies
This research investigates how genetic, epigenetic, microbial, and metabolic factors contribute to the progression of inflammatory bowel disease (IBD) in African Americans. By analyzing differences in genetic markers and their effects on disease outcomes, the study aims to develop a better understanding of how lifestyle factors like diet and alcohol consumption influence IBD. Patients will be evaluated through various assessments, including genomic analysis and microbiome profiling, to identify risk factors specific to the African American population. The goal is to create tailored risk assessments that can improve patient management and outcomes.
Why it matters
Potential benefit: If successful, this research could lead to more personalized treatment strategies for African Americans suffering from inflammatory bowel disease.
How similar studies have gone: Previous research has shown promising results in understanding genetic and environmental factors in IBD, but this specific focus on African Americans is relatively novel.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Kugathasan, Subra — Emory University
- Study coordinator: Kugathasan, Subra
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.