Understanding Genes for Acute Myeloid Leukemia Outcomes
Genomics of AML Prognosis
This project looks at the genetic makeup of patients with Acute Myeloid Leukemia (AML) to understand why some respond better to treatment than others.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Florida NIH-funded |
| Lab location | 1 site (Gainesville, United States) |
| Project ID | NIH-11124101 on NIH RePORTER |
What this research studies
Acute Myeloid Leukemia (AML) is a serious blood cancer where current treatments don't work for everyone, especially older patients, and many experience relapse. This project aims to uncover genetic differences that influence how well patients respond to standard chemotherapy. Researchers are using advanced genetic analysis techniques to identify specific molecular markers that predict treatment success or failure. By understanding these genetic factors, we hope to personalize treatments and improve outcomes for patients with AML.
Who could benefit from this research
Good fit: This research focuses on patients diagnosed with Acute Myeloid Leukemia (AML), particularly those 21 years and older.
Not a fit: Patients without Acute Myeloid Leukemia or those not undergoing standard chemotherapy for AML would not directly benefit from this specific genetic prognosis research.
Why it matters
Potential benefit: If successful, this work could lead to more personalized treatment plans for AML patients, helping doctors choose the most effective therapies and potentially improving survival rates.
How similar studies have performed: The principal investigators have a decade of successful collaboration, including publications and patents, in developing methods and discovering molecular prognostic factors for AML.
Where this research is happening
Gainesville, United States
- University of Florida — Gainesville, United States (Active)
Researchers
- Principal investigator: Lamba, Jatinder K. — University of Florida
- Study coordinator: Lamba, Jatinder K.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.