Understanding Genes and Gut Health for Bone Weakness
Official title: Trans-omics Integration of Multi-omics Studies for Osteoporosis
Funded at Tulane University of Louisiana · NIH-11118815 · Data updated 2026-11-12
This project explores how our genes and gut bacteria work together to affect bone strength and the risk of osteoporosis.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Tulane University of Louisiana NIH-funded |
| Lab location | 1 site (New Orleans, United States) |
| Project start | September 15, 2017 |
| Project end | June 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $2,076,736 |
| NIH project number | 5U19AG055373-09 |
| Project ID | NIH-11118815 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals with or at risk for osteoporosis, particularly those who have participated in studies like the Louisiana Osteoporosis Study, may be relevant to this research.
✕Less likely to help
Patients whose bone health issues are not primarily related to genetic or gut microbiome factors may not directly benefit from this specific line of research.
What this research studies
This project aims to uncover the many factors that contribute to osteoporosis, a common bone-weakening condition. We are looking closely at how your genes, the bacteria in your gut, and even your environment might influence bone formation and breakdown. Our goal is to understand the specific ways these elements interact to increase or decrease your risk of developing osteoporosis and bone fractures. This work builds on previous findings and uses existing patient information to help us find new ways to prevent and treat this condition.
Why it matters
Potential benefit: If successful, this work could lead to new ways to identify individuals at high risk for osteoporosis and develop more personalized prevention and treatment strategies.
How similar studies have gone: This project builds upon previous successful research in understanding osteoporosis and utilizes established patient data.
Where this research is happening
-
Tulane University of Louisiana
New Orleans, United States Active
Researchers
- Principal investigator: Deng, Hong-Wen — Tulane University of Louisiana
- Study coordinator: Deng, Hong-Wen
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.