Understanding gene networks that influence facial development in pupfishes
Official title: Novel gene regulatory networks underlying two specialized modes of craniofacial development in a new model system of pupfishes
Funded at University of California Berkeley · NIH-10949484 · Data updated 2026-11-12
This study looks at how genes shape the different facial features of pupfish, helping us understand the genetic reasons behind their unique appearances, which could also give us clues about human health.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Berkeley NIH-funded |
| Lab location | 1 site (Berkeley, United States) |
| Project start | August 8, 2024 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $148,176 |
| NIH project number | 1K99DE034058-01 |
| Project ID | NIH-10949484 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would include individuals with craniofacial anomalies or those interested in genetic studies related to facial development.
✕Less likely to help
Patients who do not have craniofacial conditions or genetic concerns may not receive direct benefits from this research.
What this research studies
This research investigates the genetic factors that contribute to the unique facial structures of different pupfish species. By studying these fish, researchers aim to identify specific gene regulatory networks that control craniofacial development. The project utilizes advanced techniques like ATAC sequencing to analyze how gene expression varies among species with different feeding adaptations. This work could provide insights into the genetic basis of craniofacial diversity, which may have implications for human health.
Why it matters
Potential benefit: If successful, this research could lead to a better understanding of genetic factors influencing craniofacial conditions in humans.
How similar studies have gone: Previous research has shown success in using model organisms to uncover genetic mechanisms related to craniofacial development, suggesting this approach could yield valuable insights.
Where this research is happening
-
University of California Berkeley
Berkeley, United States Active
Researchers
- Principal investigator: Palominos Chacon, Maria Fernanda — University of California Berkeley
- Study coordinator: Palominos Chacon, Maria Fernanda
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.