Understanding gene networks related to cigarette smoking and opioid addiction.
Integrating Multiple Omics to Illuminate Gene Networks Underlying Cigarette Smoking and Opioids.
This study is looking at how our genes might influence addiction to smoking and opioids, using advanced technology to analyze genetic information from both living people and brain samples, with the hope of finding better ways to treat these addictions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Research Triangle Institute NIH-funded |
| Lab location | 1 site (Research Triangle Park, United States) |
| Project ID | NIH-10873140 on NIH RePORTER |
What this research studies
This research aims to uncover the genetic networks that contribute to addiction behaviors, specifically focusing on cigarette smoking and opioid use. By utilizing a novel framework called Gene Network Identification and Integration (GNetII), the study will analyze a combination of genetic data from living individuals and postmortem brain samples. The approach includes advanced techniques such as genome-wide association studies and artificial intelligence to identify unique and shared genetic factors associated with these addictions. This research could provide insights into the biological underpinnings of addiction, potentially leading to more effective treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with a history of cigarette smoking or opioid use, particularly those who are 21 years or older.
Not a fit: Patients who do not have a history of cigarette smoking or opioid use may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for individuals struggling with addiction to cigarettes and opioids.
How similar studies have performed: Other research has shown success in identifying genetic factors related to addiction, making this approach promising yet still innovative.
Where this research is happening
Research Triangle Park, United States
- Research Triangle Institute — Research Triangle Park, United States (Active)
Researchers
- Principal investigator: Hancock, Dana B — Research Triangle Institute
- Study coordinator: Hancock, Dana B
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.