Understanding gene functions in lesser-known fungi
Discovery of gene function and dissection of network re-wiring in non-model fungi
This study is looking at how certain genes in the fungus Candida auris work and change over time, which could help us understand this emerging infection better and find new ways to treat it.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-10899739 on NIH RePORTER |
What this research studies
This research focuses on uncovering the functions of genes in non-model fungi, particularly Candida auris, which is an emerging fungal pathogen. By using advanced computational models and high-throughput transcriptomic studies, the researchers aim to create detailed models that predict how changes in gene function affect fungal behavior. The study will also explore how regulatory networks in these fungi can change over time, providing insights into their biology and responses to environmental factors. This work is crucial for developing a deeper understanding of fungal biology and could have implications for treating fungal infections.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals affected by infections caused by Candida auris or those at risk of such infections.
Not a fit: Patients with fungal infections caused by well-studied fungi may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing and treating infections caused by Candida auris and similar fungi.
How similar studies have performed: While the approach of studying gene functions in non-model fungi is relatively novel, similar methodologies have shown promise in other areas of fungal research.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Omeara, Teresa R. — University of Michigan at Ann Arbor
- Study coordinator: Omeara, Teresa R.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.