Understanding gastroparesis in children and teens
Official title: Advancing Clinical Science in Pediatric Gastroparesis
Funded at Baylor College of Medicine · NIH-11337071 · Data updated 2026-11-12
This project is building a national registry to learn more about gastroparesis and similar stomach conditions in children and adolescents.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | September 25, 2016 |
| Project end | July 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $317,987 |
| NIH project number | 3U01DK112194-09S1 |
| Project ID | NIH-11337071 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children and adolescents with diagnosed or suspected gastroparesis, chronic nausea-vomiting, cyclic vomiting, or pediatric functional dyspepsia are the best candidates for participation.
✕Less likely to help
This is not a treatment trial, so people seeking immediate therapy or those whose symptoms are caused by a mechanical obstruction or unrelated conditions are unlikely to gain direct benefit from joining the registry.
What this research studies
If your child joins, the team will collect medical history, symptom reports, and quality-of-life information over time into a national registry. They will use pediatric diagnostic criteria to group children with gastroparesis and related conditions like functional dyspepsia, chronic nausea-vomiting, and cyclic vomiting. Participating centers may also share test results and track treatments and outcomes to identify factors linked with worse symptoms and lower quality of life. The registry is designed to create child-specific knowledge that can guide better care and future clinical trials.
Why it matters
Potential benefit: If successful, this work could lead to clearer diagnoses, more tailored treatments, and better-designed clinical trials for children with gastroparesis and related conditions.
How similar studies have gone: Adult gastroparesis registries and the NIDDK Gastroparesis Consortium have improved understanding in adults, but pediatric registry work is limited and this project builds on prior efforts to fill that gap.
Where this research is happening
-
Baylor College of Medicine
Houston, United States Active
Researchers
- Principal investigator: Preidis, Geoffrey a — Baylor College of Medicine
- Study coordinator: Preidis, Geoffrey a
Related research
Other NIH-funded projects on the same topics.
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New England Gastroparesis Consortium: Neurobiology of Gastroparesis
A national project to learn about gastroparesis in children and adults by creating a registry and gathering information from patients to understand symptoms, quality of life, and disease progression.
-
Pediatric and Young Adult Gastroparesis Registry and Disease Course
This project follows children, teens, and young adults with symptoms of gastroparesis to learn how their symptoms change over time and what factors are tied to different disease patterns.
-
Pediatric gastroparesis: building a nationwide patient registry
This grant funds a national registry to study gastroparesis and similar tummy problems in children and teens, with the goal of better understanding how the condition affects their daily lives.
-
Gut-resident macrophages and gastric function in gastroparesis
A study in people with gastroparesis to understand how gut macrophages affect stomach movement and gut barrier health, with the hope of finding new ways to treat the condition.
-
Gastric electrical stimulation for stomach pain in gastroparesis
A new approach tests how adjusting a stomach-stimulating implant may reduce pain for people with gastroparesis.
-
Peptide therapies for gastroparesis in diabetes
A new peptide-based treatment is being tested to help people with gastroparesis linked to diabetes by improving stomach emptying and reducing inflammation.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.