Understanding gastrointestinal issues in autistic individuals and predicting treatment responses

Characterizing gastrointestinal disorder trajectories for autistic sub-groups: Machine learning prediction of risk profiles and response to treatment

NIH-funded research University of Southern California · NIH-11142549

This study is looking into the tummy troubles that many autistic people and their families experience, trying to figure out how these issues change over time, so we can find better ways to help everyone feel better.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Southern California NIH-funded
Lab location1 site (Los Angeles, UNITED STATES)
Project IDNIH-11142549 on NIH RePORTER

What this research studies

This research investigates the gastrointestinal (GI) problems commonly reported by autistic individuals and their families, aiming to understand how these symptoms develop over time. By combining qualitative interviews with autistic adults and caregivers, along with quantitative analysis of electronic health records, the study seeks to identify risk profiles and treatment responses among different sub-groups of autistic individuals. The use of machine learning will help create predictive models that can inform better treatment strategies tailored to individual needs.

Who could benefit from this research

Good fit: Ideal candidates for this research include autistic individuals of all ages, particularly those experiencing gastrointestinal symptoms, as well as their caregivers.

Not a fit: Patients without gastrointestinal issues or those not on the autism spectrum may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and management of gastrointestinal issues in autistic individuals, enhancing their overall health and quality of life.

How similar studies have performed: Previous research has shown promise in using machine learning and qualitative methods to understand health trajectories in various populations, suggesting potential for success in this novel approach.

Where this research is happening

Los Angeles, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions adolescent with autism spectrum disorderadult with autism spectrum disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.