Understanding gastrointestinal issues from oral immunotherapy for food allergies
Mechanisms of adverse gastrointestinal events during oral immunotherapy
This study is looking into the tummy troubles some people with food allergies might have when they try oral immunotherapy, and it aims to find ways to prevent these issues so that treatment can be better for everyone dealing with food allergies and related gut problems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Arizona NIH-funded |
| Lab location | 1 site (Scottsdale, United States) |
| Project ID | NIH-10890093 on NIH RePORTER |
What this research studies
This research focuses on the gastrointestinal side effects that can occur during oral immunotherapy (OIT) for food allergies, particularly eosinophilic esophagitis (EoE). The project aims to investigate the underlying mechanisms of these adverse effects and develop strategies to prevent them. Dr. Benjamin Wright, the principal investigator, will acquire training in clinical study design and basic research techniques to enhance patient care in this area. The ultimate goal is to improve treatment outcomes for individuals suffering from food allergies and related gastrointestinal disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with food allergies, particularly those experiencing gastrointestinal issues like eosinophilic esophagitis.
Not a fit: Patients without food allergies or those not experiencing gastrointestinal side effects from oral immunotherapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer oral immunotherapy treatments with fewer gastrointestinal side effects for patients with food allergies.
How similar studies have performed: Previous research has shown promise in understanding the mechanisms of food allergies and their treatments, but this specific focus on gastrointestinal side effects during oral immunotherapy is relatively novel.
Where this research is happening
Scottsdale, United States
- Mayo Clinic Arizona — Scottsdale, United States (Active)
Researchers
- Principal investigator: Wright, Benjamin L. — Mayo Clinic Arizona
- Study coordinator: Wright, Benjamin L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.