Understanding gastrointestinal diseases in children with cystic fibrosis

Gastrointestinal Biology Core

NIH-funded research Dartmouth College · NIH-10914649

This study is looking at how gut bacteria affect kids with cystic fibrosis to help find better treatments and improve their health.

Quick facts

Grant typeP30 center grant
Study typeNIH-funded research
Funding institutionDartmouth College NIH-funded
Lab location1 site (Hanover, United States)
Project IDNIH-10914649 on NIH RePORTER

What this research studies

This research focuses on advancing our understanding of gastrointestinal diseases, particularly in children with cystic fibrosis (CF). It utilizes various model systems, including 3D intestinal organoids and mouse models, to study the interactions between gut microbes and the host. By collaborating with clinical researchers, the project aims to develop new methodologies and analytical approaches to enhance GI research. The goal is to facilitate studies that could lead to better treatments and outcomes for patients with CF.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 0-11 years diagnosed with cystic fibrosis.

Not a fit: Patients without cystic fibrosis or those outside the age range of 0-11 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment options for gastrointestinal diseases in children with cystic fibrosis.

How similar studies have performed: Previous research has shown success in using similar model systems to study gastrointestinal diseases, indicating a promising approach.

Where this research is happening

Hanover, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.