Understanding False Alarms in Lung Cancer Screening
Lung Cancer Screening: Cumulative Risk and Multilevel Impact of False Positive Findings
['FUNDING_R01'] · UNIV OF NORTH CAROLINA CHAPEL HILL · NIH-11141221
This project looks at how often false alarms happen in lung cancer screening and how they affect patients, doctors, and healthcare systems.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIV OF NORTH CAROLINA CHAPEL HILL (nih funded) |
| Locations | 1 site (CHAPEL HILL, UNITED STATES) |
| Trial ID | NIH-11141221 on ClinicalTrials.gov |
What this research studies
The National Lung Screening Trial showed that lung cancer screening can save lives, but it also found many false-positive results. These false alarms mean you might need more tests or procedures, which can cause worry and extra costs, even if you don't have cancer. This project wants to understand the full impact of these false alarms on people like you, your doctors, and the healthcare system over time. By learning more about why false positives happen and their effects, we hope to make lung cancer screening better and less stressful for everyone.
Who could benefit from this research
Good fit: Patients who are currently undergoing or are candidates for lung cancer screening, particularly those aged 50-80 with a significant smoking history, would be ideal.
Not a fit: Individuals who are not candidates for lung cancer screening based on age or smoking history would not directly benefit from this particular research.
Why it matters
Potential benefit: If successful, this work could lead to improved lung cancer screening methods that reduce unnecessary worry and procedures for patients.
How similar studies have performed: While lung cancer screening efficacy is established, this specific focus on the cumulative and multilevel impact of false positives in real-world settings is a novel area of investigation.
Where this research is happening
CHAPEL HILL, UNITED STATES
- UNIV OF NORTH CAROLINA CHAPEL HILL — CHAPEL HILL, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HENDERSON, LOUISE — UNIV OF NORTH CAROLINA CHAPEL HILL
- Study coordinator: HENDERSON, LOUISE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.