Understanding factors that lead to successful lung transplant outcomes

Clinical and Biological Factors Predicting Lung Transplant Textbook Outcomes (U01)

NIH-funded research Duke University · NIH-10893994

This study is looking at what helps people have the best possible results after lung transplant surgery, so they can recover well and avoid complications, and it's for anyone considering or preparing for a lung transplant.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionDuke University NIH-funded
Lab location1 site (Durham, United States)
Project IDNIH-10893994 on NIH RePORTER

What this research studies

This research investigates the clinical and biological factors that predict successful outcomes after lung transplantation, focusing on minimizing early post-operative complications. By analyzing data from multiple respected lung transplant centers, the study aims to identify key characteristics that contribute to achieving ideal surgical outcomes, known as 'textbook outcomes'. The research will utilize a combination of clinical assessments and biological evaluations to better understand how these factors influence patient survival and healthcare costs.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals aged 21 and older who are undergoing or considering lung transplantation.

Not a fit: Patients who are not candidates for lung transplantation or those with significant comorbidities may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved lung transplant outcomes and reduced complications for patients.

How similar studies have performed: Previous research has shown variability in lung transplant outcomes, indicating that understanding these factors could lead to significant improvements in patient care.

Where this research is happening

Durham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.