Understanding factors that lead to opioid relapse after treatment
Prediction of Return to Opioid Use During Immediate Community Reintegration
This study is looking at how people recovering from opioid use disorder can stay on track after treatment, especially by understanding how symptoms of PTSD and physical responses like heart rate can predict if someone might relapse, so we can find better ways to support them during this important time.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rhode Island Hospital NIH-funded |
| Lab location | 1 site (Providence, United States) |
| Project ID | NIH-10923924 on NIH RePORTER |
What this research studies
This research investigates the critical period of community reintegration for individuals recovering from opioid use disorder (OUD) after residential treatment. It focuses on identifying real-time predictors that may indicate a return to opioid use, particularly examining the role of post-traumatic stress disorder (PTSD) symptoms and physiological responses such as heart rate variability and electrodermal response. By utilizing ecological monitoring tools, the study aims to track these factors closely over time to develop effective prevention strategies during this vulnerable phase. The goal is to provide insights that can help reduce the risk of relapse shortly after treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have recently completed residential treatment for opioid use disorder and are transitioning back into the community.
Not a fit: Patients who are not recovering from opioid use disorder or those who have not undergone recent treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention strategies that significantly reduce the likelihood of relapse for individuals recovering from opioid use disorder.
How similar studies have performed: While there has been research on opioid relapse, this approach utilizing real-time ecological monitoring during community reintegration is relatively novel and has not been extensively tested.
Where this research is happening
Providence, United States
- Rhode Island Hospital — Providence, United States (Active)
Researchers
- Principal investigator: Weiss, Nicole Holland — Rhode Island Hospital
- Study coordinator: Weiss, Nicole Holland
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.