Understanding factors that influence early pregnancy success
Official title: Immunological, epigenetic and developmental determinants of early pregnancy success
Funded at University of California, San Francisco · NIH-11095868 · Data updated 2026-11-12
This study is looking into how different factors in the body, like the immune system and genetics, can impact the success of early pregnancy, with the goal of finding better ways to help women who are having trouble getting pregnant.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | August 1, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $1,650,001 |
| NIH project number | 5P50HD112034-03 |
| Project ID | NIH-11095868 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include women of childbearing age who are experiencing difficulties with conception or have a history of adverse pregnancy outcomes.
✕Less likely to help
Patients who are not trying to conceive or those with infertility due to male factors may not benefit directly from this research.
What this research studies
This research investigates the complex biological mechanisms that affect early pregnancy success, particularly focusing on the roles of immune responses, genetic factors, and developmental processes in the uterus. By examining how these elements interact, the research aims to identify potential diagnostic markers and personalized treatment options for women facing challenges with fertility. The study involves collaboration among various scientific disciplines and aims to enhance public understanding of reproductive health. It also emphasizes the importance of including diverse voices in the research community.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostics and personalized therapies for women experiencing infertility and related complications during pregnancy.
How similar studies have gone: Previous research has shown promise in understanding reproductive health through similar interdisciplinary approaches, indicating potential for success in this area.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Erlebacher, Adrian — University of California, San Francisco
- Study coordinator: Erlebacher, Adrian
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.