Understanding factors that increase cancer risk
Official title: PROMINENT - IARC
Funded at International Agency for Res on Cancer · NIH-10625615 · Data updated 2026-11-12
This study is looking at how things like your lifestyle and environment, not just DNA changes, can affect your risk of getting cancer, and it hopes to find new ways to help people lower that risk.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | International Agency for Res on Cancer NIH-funded |
| Lab location | 1 site (Lyon, France) |
| Project start | June 22, 2022 |
| Project end | May 31, 2026 |
| Funding year | 2022 |
| Award (this year) | $391,529 |
| NIH project number | 1OT2CA278681-01 |
| Project ID | NIH-10625615 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals concerned about their cancer risk due to lifestyle or environmental factors.
✕Less likely to help
Patients with hereditary cancer syndromes may not benefit directly from this research.
What this research studies
This research investigates the various factors that contribute to cancer risk beyond just DNA mutations. It focuses on identifying non-mutagenic factors, such as lifestyle choices and environmental influences, that may play a critical role in cancer development. By studying both human populations and mouse models, the research aims to uncover the mechanisms that lead to cancer, potentially leading to new prevention strategies. Patients may benefit from insights that could inform lifestyle changes or interventions to reduce their cancer risk.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for cancer prevention by identifying modifiable risk factors.
How similar studies have gone: Other research has shown success in identifying lifestyle factors that influence cancer risk, making this approach promising.
Where this research is happening
-
International Agency for Res on Cancer
Lyon, France Active
Researchers
- Principal investigator: Brennan, Paul Joseph — International Agency for Res on Cancer
- Study coordinator: Brennan, Paul Joseph
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.