Understanding factors that affect treatment outcomes for teens with substance use issues

Neural, genetic, and environmental indicators of treatment outcomes for adolescent substance use

NIH-funded research Rutgers Biomedical and Health Sciences · NIH-11056061

This study is looking at how genes, brain activity, and life experiences affect how well treatments work for teens dealing with substance use, so we can create more personalized and effective care for them.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionRutgers Biomedical and Health Sciences NIH-funded
Lab location1 site (Newark, UNITED STATES)
Project IDNIH-11056061 on NIH RePORTER

What this research studies

This research investigates how genetic, neural, and environmental factors influence the effectiveness of treatments for adolescents struggling with substance use and related behaviors. By analyzing data from the Adolescent Brain Cognitive Development study, the project aims to identify key neural networks and their relationship with genetic and environmental risks. The goal is to enhance personalized treatment approaches, making them more effective and tailored to individual needs. This research combines advanced neuroscience methods with clinical practice to improve outcomes for affected youth.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents who are currently experiencing substance use problems and related externalizing behaviors.

Not a fit: Patients who are not adolescents or those who do not have substance use issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and personalized treatment strategies for adolescents dealing with substance use issues.

How similar studies have performed: Previous research has shown promise in using neuroimaging and genetic data to inform treatment strategies, suggesting that this approach could yield valuable insights.

Where this research is happening

Newark, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.