Understanding factors that affect treatment outcomes for teens with substance use issues
Official title: Neural, genetic, and environmental indicators of treatment outcomes for adolescent substance use
Funded at Rutgers Biomedical and Health Sciences · NIH-11056061 · Data updated 2026-11-12
This study is looking at how genes, brain activity, and life experiences affect how well treatments work for teens dealing with substance use, so we can create more personalized and effective care for them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers Biomedical and Health Sciences NIH-funded |
| Lab location | 1 site (Newark, UNITED STATES) |
| Project start | April 1, 2024 |
| Project end | March 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $177,118 |
| NIH project number | 5K23DA058808-02 |
| Project ID | NIH-11056061 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adolescents who are currently experiencing substance use problems and related externalizing behaviors.
✕Less likely to help
Patients who are not adolescents or those who do not have substance use issues may not benefit from this research.
What this research studies
This research investigates how genetic, neural, and environmental factors influence the effectiveness of treatments for adolescents struggling with substance use and related behaviors. By analyzing data from the Adolescent Brain Cognitive Development study, the project aims to identify key neural networks and their relationship with genetic and environmental risks. The goal is to enhance personalized treatment approaches, making them more effective and tailored to individual needs. This research combines advanced neuroscience methods with clinical practice to improve outcomes for affected youth.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment strategies for adolescents dealing with substance use issues.
How similar studies have gone: Previous research has shown promise in using neuroimaging and genetic data to inform treatment strategies, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Rutgers Biomedical and Health Sciences
Newark, United States Active
Researchers
- Principal investigator: Brislin, Sarah — Rutgers Biomedical and Health Sciences
- Study coordinator: Brislin, Sarah
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.