Understanding factors that affect brain health and cognitive function
Official title: Integrative Pathways to Cognitive, Affective, and Brain Health
Funded at University of Wisconsin-Madison · NIH-10894236 · Data updated 2026-11-12
This study is looking at what helps protect against or increases the risk of memory loss and Alzheimer's Disease by gathering information from a wide range of adults aged 25 to 95, so we can better understand how different life factors affect brain health over time.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project start | September 30, 2022 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $3,687,091 |
| NIH project number | 5U01AG077928-03 |
| Project ID | NIH-10894236 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adults aged 25 to 95 who are interested in understanding their cognitive health and contributing to advancements in Alzheimer's prevention.
✕Less likely to help
Patients with advanced Alzheimer's Disease or severe cognitive impairment may not benefit from this research.
What this research studies
This research investigates the risk and protective factors associated with cognitive decline and Alzheimer's Disease (AD) through comprehensive assessments of behavioral, social, psychological, and biological data collected over decades. Participants will undergo cognitive assessments and neuroimaging to identify early markers of cognitive impairment and emotional processing. The study aims to gather data from a diverse group of adults aged 25 to 95, focusing on how these factors influence brain health over time.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for preventing cognitive decline and Alzheimer's Disease.
How similar studies have gone: Previous research has shown success in identifying cognitive decline markers using similar comprehensive assessment approaches.
Where this research is happening
-
University of Wisconsin-Madison
Madison, United States Active
Researchers
- Principal investigator: Ryff, Carol D. — University of Wisconsin-Madison
- Study coordinator: Ryff, Carol D.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.