Understanding factors that affect brain health and cognitive function

Integrative Pathways to Cognitive, Affective, and Brain Health

['FUNDING_U01'] · UNIVERSITY OF WISCONSIN-MADISON · NIH-10894236

This study is looking at what helps protect against or increases the risk of memory loss and Alzheimer's Disease by gathering information from a wide range of adults aged 25 to 95, so we can better understand how different life factors affect brain health over time.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF WISCONSIN-MADISON (nih funded)
Locations1 site (MADISON, UNITED STATES)
Trial IDNIH-10894236 on ClinicalTrials.gov

What this research studies

This research investigates the risk and protective factors associated with cognitive decline and Alzheimer's Disease (AD) through comprehensive assessments of behavioral, social, psychological, and biological data collected over decades. Participants will undergo cognitive assessments and neuroimaging to identify early markers of cognitive impairment and emotional processing. The study aims to gather data from a diverse group of adults aged 25 to 95, focusing on how these factors influence brain health over time.

Who could benefit from this research

Good fit: Ideal candidates for this research include adults aged 25 to 95 who are interested in understanding their cognitive health and contributing to advancements in Alzheimer's prevention.

Not a fit: Patients with advanced Alzheimer's Disease or severe cognitive impairment may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing cognitive decline and Alzheimer's Disease.

How similar studies have performed: Previous research has shown success in identifying cognitive decline markers using similar comprehensive assessment approaches.

Where this research is happening

MADISON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.