Understanding factors contributing to Alzheimer's Disease diversity
Clinical Core
This study is looking at how Alzheimer's Disease shows up differently in people and is inviting a diverse group of participants, especially African Americans, to help us learn more about the disease by collecting samples and images to find important clues.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10870017 on NIH RePORTER |
What this research studies
This research investigates the various factors that influence the differences in how Alzheimer's Disease (AD) manifests in individuals. It aims to recruit a diverse group of participants, including those with mild dementia and other neurodegenerative conditions, to better understand the disease's heterogeneity. The study will involve collecting and analyzing biological samples and imaging data to identify key markers associated with AD. A particular focus is placed on including African American individuals, who are often underrepresented in AD research, to enhance the understanding of how demographic factors affect disease expression.
Who could benefit from this research
Good fit: Ideal candidates for participation include cognitively normal older adults and individuals with mild dementia, particularly those from African American backgrounds.
Not a fit: Patients with advanced stages of dementia or those not fitting the demographic criteria may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatments for Alzheimer's Disease based on individual characteristics.
How similar studies have performed: Previous research has shown success in understanding Alzheimer's Disease through diverse cohort studies, indicating that this approach is promising.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Wolk, David a — University of Pennsylvania
- Study coordinator: Wolk, David a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.