Understanding factors affecting the integrity of the jaw joint over time

Predictive Markers for Longitudinal TMJ Integrity

NIH-funded research State University of New York at Buffalo · NIH-10920362

This study is looking at what causes problems with the jaw joint (TMJ) and how these issues might be different for men and women, so we can better understand and track the health of people with jaw pain over time.

Quick facts

Grant typeR03 grant
Study typeNIH-funded research
Funding institutionState University of New York at Buffalo NIH-funded
Lab location1 site (Amherst, United States)
Project IDNIH-10920362 on NIH RePORTER

What this research studies

This research investigates the factors that contribute to the deterioration of the temporomandibular joint (TMJ), particularly focusing on how these factors may differ between males and females. By analyzing the mechanics and behaviors that influence TMJ tissue fatigue, the study aims to identify predictive markers that can help in understanding the progression of temporomandibular disorders (TMDs). The research utilizes a scoring system to quantify energy input to TMJ tissues and correlates these findings with anatomical and psychological variables that are easier to measure in clinical settings. Patients may be monitored over several years to assess changes in their TMJ health based on these predictive markers.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals experiencing symptoms of temporomandibular disorders, particularly those who are female or have a family history of TMJ issues.

Not a fit: Patients who do not have temporomandibular disorders or related symptoms may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment strategies for patients suffering from temporomandibular disorders.

How similar studies have performed: Previous research has shown promising results in identifying predictive markers for joint integrity, suggesting that this approach may yield valuable insights.

Where this research is happening

Amherst, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.